Українська Abstract
Ashwagandha-based preparations are gaining increasing global popularity as effective natural therapeutic agents. However, the lack of consensus regarding the scientific validity of this plant’s effects and the absence of comprehensive biochemical studies highlight the need for a systematic analysis of its efficacy, particularly within the framework of evidence-based medicine. The purpose of this study was to assess the effectiveness of ashwagandha-based preparations through the analysis of experimental research. To achieve this, a systematic review and analysis of literature sources from scientific databases were conducted using an analytical approach. A range of experimental studies demonstrate that the application of the leaves and roots of two ashwagandha species, Withania somnifera and Withania coagulans, is the most effective. Both aqueous extracts and alcohol-based extracts exhibit comparable therapeutic value. The most commonly available formulations are in capsule or tablet form. Notably, a positive impact and improvements in cognitive functions, psychological well-being, and physical performance have been observed among volunteers participating in experiments. Improvements have also been reported in conditions such as depression, anxiety, hormonal imbalances, muscle weakness, and sexual dysfunction. The antioxidant and anti-inflammatory properties of Withania somnifera contribute to slowing down ageing processes, inhibiting tumour development, and supporting the proper functioning of the cardiovascular, nervous, and muscular systems. Combined preparations containing ashwagandha demonstrate particularly high efficacy, enhancing the studied health parameters. Furthermore, incorporating this herbal extract into primary medical treatments has been shown to accelerate patient recovery. Importantly, ashwagandha is not contraindicated for older adults; on the contrary, experimental evidence suggests that its consumption reduces muscle atrophy, improves overall well-being, and regulates hormonal balance in elderly men. According to experimental findings, ashwagandha possesses a range of therapeutic properties that can substantially improve human health indicators, particularly in men. Therefore, the integration of this medicinal plant into contemporary medical practice may yield highly beneficial results
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